I recently read this article from http://biosyntrx.com/Article.php?ArticleID=287 on instigators of aging and how these minerals can help with oxidative damage to the eye. Thought I would share with you!



Instigators of Aging


May 7th, 2010


Scientists have suspected for more than 50 years that reactive oxygen species (ROS) is one of the major instigators of aging. These oxygen byproducts of metabolism wreak havoc with a large number of molecules, as well as inhibit the body’s ability to repair the damage they cause.

All tissues are vulnerable to oxidative damage, but because most ROS arise from normal metabolic processes, the more active tissues suffer the most, and that includes tissues in the retina and the brain.

These bad boys crash around inside and outside the cell, destroying molecules in their path. They attack lipid fatty acids, eventually decreasing their numbers enough to reduce membrane fluidity and that is the beginning of big problems, particularly for those genetically susceptible to macular degeneration, Alzheimer’s and Parkinson’s disease..

To cope with this problem, evolution has provided protective enzymes, particularly, superoxide dismutase (SOD and SOD2). These enzymes differ both in the type of metal found in their active sites and in their cellular locations. The SOD enzyme is made from dietary copper and zinc (Cu/Zn), which inhabits the extra-cellular spaces only.

SOD2 (also called MnSOD) dwells inside the mitochondria matrix, where the majority of cellular adenosine triphosphate (ATP) metabolic energy is formed, as well as where the majority of oxidation (free radical formation) takes place. ATP is vital for ribonucleic acid (RNA) synthesis. RNA, just in case you’ve forgotten, transfers information from our unique DNA to the protein-forming system of all cells.

Manganese must be present in the diet, along with copper and zinc, to produce SOD2 (MnSOD) enzymes. These enzymes help protect retina and brain mitochondria from destructive free radical damage.


Ellen Troyer, MT, MA –

Biosyntrx CEO/ Chief Research Officer


Leave a Comment